Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics

Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics

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AimsTo investigate the differences between 0.2 and 0.15% brimonidine tartrate eye drops for anti-mydriatic effects and the optical quality under different light conditions.

MethodsThis prospective study involved click here 80 consecutive high myopia patients undergoing implantation of a V4c ICL.The patients were randomly instilled with brimonidine 0.2 and 0.

15% 2 weeks postoperatively.Visual quality, pupil center, pupil size, and refraction under different light conditions were measured before and 0.5 h after brimonidine administration.

A symptom questionnaire was also evaluated.ResultsThere was no statistical difference in the static and dynamic pupil diameters and velocity after LS between the two groups (p > 0.05).

The 0.2% group had significant changes in pupil center before and after treatment, while there was no obvious movement of the 0.15% group under all illumination condition (p > 0.

05).The OSI after treatment of the 0.15% group was lower than that of 0.

2% group (p = 0.012).The PVA9% and PVA100% of the 0.

15% group was higher than that of 0.2% group in the dark (p = 0.009, p = 0.

012).The HOA RMS of the 0.15% group was lower than that of 0.

2% group (p = 0.016).The QIRC score in the 0.

15% group was significantly higher than that in the 0.2% group (p = 0.043).

Conclusion0.15 and 0.2% brimonidine tartrate eye drops had similar sukin body lotion woolworths anti-mydriatic ability, while 0.

15% group had better visual quality than 0.2% concentration, and hardly introduced pupil shift.0.

15% brimonidine tartrate eye drops may be more suitable for patients with nocturnal glare symptoms in the early postoperative period after ICL implantation.